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Test Code CDP Chlordiazepoxide and Metabolite, Serum

Test Down Notes

Effective December 14, 2023: This test is temporarily unavailable due to analytic issues. The downtime is expected to be >30 days. Order ZW86, (1080SP) as an alternate.  See test notification here.

Reporting Name

Chlordiazepoxide and metabolite, S

Useful For

Monitoring chlordiazepoxide therapy

 

Assessing toxicity

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Shipping Instructions


Ship specimen in amber vial to protect from light.



Specimen Required


Supplies: Amber Frosted Tube, 5 mL (T915)

Collection Container/Tube: Red top

Submission Container/Tube: Amber vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into amber vial within 2 hours of collection.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 14 days LIGHT PROTECTED
  Frozen  14 days LIGHT PROTECTED
  Ambient  24 hours LIGHT PROTECTED

Reference Values

Therapeutic concentration:

Chlordiazepoxide: 400-3,000 ng/mL

Nordiazepam: 100-500 ng/mL

Day(s) Performed

Monday, Wednesday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CDP Chlordiazepoxide and metabolite, S 33060-5

 

Result ID Test Result Name Result LOINC Value
8610 Chlordiazepoxide 3457-9
37321 Nordiazepam 3537-8

Report Available

2 to 7 days

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Neurology Specialty Testing Client Test Request (T732)

-Therapeutics Test Request (T831)